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Scientists Find Genetic Mutation That Could Increase the Male Lifespan. Professor S. Jay Olshansky once told Gizmodo, “In the world of aging sciences, if you want to live a long life, choose long- lived parents.” So genetic markers linked to longevity are interesting as hell. But if you’ve got the wrong genes, then the wrong moves might do you in. A team of researchers from universities in the United States wanted to figure out the role of genetics in human lifespan, specifically relating to growth hormone. The researchers’ work shows two main things: first, that a mutation in men’s DNA relating to growth hormone might lead to a longer lifespan. And secondly, that treating older people with growth hormone might be dangerous if they don’t have the variation. Gil Atzmon, the study’s principal investigator from Albert Einstein College of Medicine and the University of Haifa in Israel, was most excited by how a slight change in DNA could have such a big impact. Delete a few base pairs, “and you still have a functional protein that now makes people live longer,” he said. Basically, there’s one system in question, the “IGF- 1/GH axis.” Each of these are genes that code for different molecules in your body. Researchers have already had a hunch that IGF- 1 can regulate height at the expense of longevity, like the case in dogs. More IGF- 1 means taller but shorter lifespan and less IGF- 1 means shorter but longer lifespan. This should make sense—it’s akin to the way big dogs live shorter lives than small dogs. The researchers studied 8. Indeed, the IGF- 1 levels were lower in the centenarians, but many of the men were also taller. The data showed the researchers that there’s more than just IGF- 1 at play. Centenarian males were often missing a specific snippet of DNA in their GHR gene. These people seem to be more sensitive to growth hormone and grow taller. So, even though their IGF- 1 levels were lower (they lived longer), they still grew taller from their special GH gene. The people with this mutation seemed to live ten years longer, on average. And the study really was huge. The replication across the four different populations “makes our result more accurate and globally translated.” Atzmon himself admitted that all this is pretty complex. But it’s definitely new, important evidence pointing to the role that this IGF- 1/GH axis plays in simultaneously determining your height and your lifespan, explained Andrzej Bartke, Professor of Physiology and Internal Medicine at Southern Illinois University School of Medicine, in a conversation with Gizmodo. But we’re not at some level of life- hacking clarity. Their results seemed to show that folks who don’t have the GH variation might actually be sensitive to growth hormone therapy. 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If you decide to stay, here is what you can expect. The First Stop - Detox. Some residential rehab facilities have their own in- house detoxification programs, but more centers today are requiring clients to complete detox prior to entering their facilities. In other words, you may need to get clean and sober before you can even enter rehab. The trend today is to have you go through the withdrawal process at a facility that specializes in dealing with drug and alcohol withdrawal symptoms. Typically, this done on a short- term, five to seven days, inpatient basis. The Facilities. Thousands of residential rehab facilities are in the United States today, and each one is different from the next as far as its physical facilities are concerned. They range from almost primitive camp- type settings - - usually for troubled teens - - to the most luxurious facilities imaginable and everything in between. Like most other things in life, you get what you pay for or what you or your insurance can afford. The type of physical facilities the program offers has little to do with how successful or effective their program might be in keeping you sober. Education. Education is the core component of all treatment and rehab programs. It may vary from facility to facility, but generally the process is aimed at getting you to look at your addiction honestly and realistically, and change your attitude about your drug and alcohol use. In the early stages of recovery, most alcoholics or addicts may still be holding on to some denial about the seriousness of their problem or may be ambivalent about quitting drugs and alcohol for good. Treatment programs try to break through that denial and ambivalence to try to get you to commit to a clean and sober lifestyle. Typically, you will learn about the nature of alcoholism and the dynamics of addiction, the effects drugs and alcohol have on your body and the consequences if you continue to use. Counseling and Group Therapy. During your rehab, you will probably receive individual counseling with a trained addictions counselor and you will possibly participate daily in group therapy meetings with others at the facility. These sessions are designed to begin to teach you the skills that you will need to live life without drugs and alcohol. You will learn how to recognize situations in which you are most likely to drink or use drugs and how to avoid these circumstances if possible. You will learn new coping skills. The group sessions are designed to teach you the value of seeking support from others who are going through the same experiences and challenges that you are. In some facilities, these group sessions may be actual 1. In other facilities, they may be facilitated by staff members. Family Meetings. Many successful drug and alcohol rehab programs will include members of your family in your treatment program. Research has shown that including family and friends in the educational process significantly improves rehab outcomes. Some programs include family members and friends throughout the entire rehab process, from the initial assessment through continued follow- up aftercare. In the family meetings, your family members will learn about the dynamics of addiction, learn to identify strengths and resources to help encourage you in your recovery, discuss how they have been affected by your substance abuse and learn how they also can begin to heal their own wounds. Many rehab facilities require family members to attend Al- Anon meetings if they want to visit you while you are in treatment, to learn how they may have been enabling you and contributing to the problem with their actions and reactions to your substance abuse. Aftercare Program. The typical residential drug and alcohol rehab program will last about 2. What happens when you have to leave the relative safety of the facility and go back into the real world? Successful rehab programs have a strong aftercare program plan designed to meet your individual needs. By now your counselor probably knows you well and will suggest the next steps to take based on where you are on your recovery journey. Your aftercare plan may include intensive outpatient treatment, residence at a halfway house, attendance at 1. For more information see: The Stages of Rehab Recovery. Sources: National Institute on Drug Abuse. Al caminar por el centro histórico de la ciudad de Chihuahua, específicamente en la esquina de las calles Ocampo y Victoria, se encuentra la tienda denominada. The timeline of some of the most relevant events in the Mexican Drug War is set out below. Although violence between drug cartels had been occurring for three decades. Tabasco - Centro. 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